Selected Publication

 

  1. Chen YT, Jhao PY, Hung CT, Wu YF, Lin SJ, Chiang WC, Lin SL, Yang KC. Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGFβ signaling in kidney fibroblasts. Journal of Clinical Investigation 2021 Jan 19;143645. doi:10.1172/JCI143645. Online ahead of print.
  2. Wang TE, Lai YH, Yang KC, Lin SJ, Chen CL, Tsai PS. Counteracting cisplatin-induced testicular damages by natural polyphenol constituent Honokiol. Antioxidants 9: E723, 2020.  
  3. Lee TH, Yeh CF, Lee YT, Shih YC, Chen YT, Huang CT, You MY, Wu PC, Shentu TP, Huang RT, Lin YS, Wu YF, Lin SJ, Lu FL, Tsao PN, Lin TH, Lo SC, Tseng YS, Wu WL, Chen CN, Wu CC, Lin SL, Sperling AI, Guzy RD, Fang Y, Yang KC*. Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization. Nature Communications 11: 4254, 2020.
  4. Huang WY, Hong JB, Chang M, Wang SY, Lai SF, Chien HF*, Lin SJ*. Lower proximal cup and outer root sheath cells regenerate hair bulbs during anagen hair follicle repair after chemotherapeutic injury. Experimental Dermatology 2020 Aug 11. doi:10.1111/exd.14175. Online ahead of print
  5. Shwartz Y#, Gonzalez-Celeiro M#, Chen CL#, Pasolli HA, Sheu SH, Fan SMY, Shamsi F, Assad S, Lin ETY, Zhang B, Tsai PC, He M, Tseng YH, Lin SJ*, Hsu YC*. Cell types promoting goosebumps form a niche to regulate hair follicle stem cells. Cell 182:578-93, 2020. (# equal contribution)
  6. Chen CL, Huang WY, Wang EHC, Kang-Yu Tai KY, Lin SJ*. Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration. Journal of Biomedical Science 27:43, 2020.
  7. Wu YF, Wang CY, Yang TL, Tsao PN, Lin SJ*, Tan HY*. Intravital multiphoton microscopic imaging platform for ocular surface imaging. Experimental Eye Research 182:194-201, 2019.
  8. Huang WY, Lin ETY, Hsu YC, Lin SJ*. Anagen hair follicle repair: timely regenerative attempts from plastic extra-bulge epithelial cells. Experimental Dermatology 28:406-412, 2019.
  9. Lee CY, Su GC, Huang WY, Ko MY, Yeh HY, Chang GD, Lin SJ, Chi P. Promotion of homology-directed DNA repair by polyamines. Nature Communications 10:65, 2019.
  10. Fan SMY, Chang YT, Chen CL, Wang WH, Pan MK, Chen WP, Huang WY, Xu Z, Huang HE, Chen T, Plikus MV, Chen SK*, Lin SJ*. External light activates hair follicle stem cells through eyes via an ipRGC-SCN-sympathetic neural pathway. Proceedings of the National Academy of Sciences of USA 115:E6880-E6889, 2018.
  11. Fan SMY, Tsai CF, Yen CM, Lin MH, Wang WH, Chan CC, Chen CL, Phua KKL, Pan SH, Plikus MV,Yu SL,Chen YJ*, Lin SJ*. Inducing hair follicle neogenesis with secreted proteins enriched in embryonic skin. Biomaterials 167:121-131, 2018.
  12. Fan SMY,Chen PH,Tseng YT, Hong JB,Chen WH,Tsai TF,Lin SJ*. Preclinical evaluation of melanocyte transplantation by chitosan-based melanocyte spheroid patch to skin prepared by controlled sunburn blistering. Journal of Biomedical Materials Research Part B: Applied Biomaterials 106:2535-2543, 2018.
  13. Huang WY, Lai SF, Chiu HY, Chang M, Plikus MV, Chan CC, Chen YT, Tsao PN, Yang TL, Lee HS, Chi P, Lin SJ*. Mobilizing transit-amplifying cell-derived ectopic progenitors prevents hair loss from chemotherapy or radiation therapy. Cancer Research 77:6083-6096, 2017 (This paper was featured by New Scientist, BioWorld and ScienceTrends)
  14. Wang WH, Chien TH, Fan SMY, Huang WY, Lai SF, Wu JT, Lin SJ*. Activation of mTORC1 signaling is required for timely hair follicle regeneration from radiation injury. Radiation Research 188:681-689, 2017.
  15. Huang WY, Huang YC, Huang KS, Chan CC, Chiu HY, Tsai RY, Chan JY, Lin SJ*. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science 86:114-122, 2017.
  16. Sheen YS, Fan SMY, Chan CC, Wu YF, Jee SH, Lin SJ*. Visible red light enhances physiological anagen entry in vivo and has direct and indirect stimulative effects in vitro. Lasers in Surgery and Medicine 47: 50-9, 2015.
  17. Lin YC, Lin MW, Yen MH, Fan SMY, Wu JT, Young TH, Cheng JY, Lin SJ*. Programmable laser-assisted surface microfabrication on a polyvinyl alcohol-coated glass chip with self-changing cell adhesivity for heterotypic cell patterning. ACS Applied Materials & Interfaces 7:22322-32, 2015.
  18. Lin SJ, Foley J, Jiang TX, Yeh CY, Wu P, Foley A, Yen CM, Huang YC, Cheng HC, Chen CF, Reeder B, Jee SH, Widelitz RB, Chuong CM. Topology of feather melanocyte progenitor niche allows complex pigment patterns to emerge. Science 340:1442-5, 2013.
  19. Huang YC, Chan CC, Lin WT, Chiu HY, Tsai RY, Tsai TH, Chan JY, Lin SJ*. Scalable production of controllable dermal papilla spheroids on PVA surfaces and the effects of spheroid size on hair follicle regeneration. Biomaterials 34:442-451, 2013.
  20. Yen CM, Chan CC, Lin SJ*. High-throughput reconstitution of epithelial-mesenchymal interaction in folliculoid microtissues by biomaterial-facilitated self-assembly of dissociated heterotypic adult cells. Biomaterials 31:4341-4352, 2010.
  21. Young TH, Tu HR, Chan CC, Huang YC, Yen MH, Cheng NC, Chiu HC, Lin SJ*. The enhancement of dermal papilla cell aggregation by extracellular matrix proteins through effects on cell-substratum adhesivity and cell motility. Biomaterials 30:5031-40, 2009.
  22. Young TH, Lee CY, Chiu HC, Hsu CJ, Lin SJ*. Self-assembly of dermal papilla cells into inductive spheroidal microtissues on poly (ethylene-co-vinyl alcohol) membranes for hair follicle regeneration. Biomaterials 29:3521-30, 2008.
  23. Lin SJ, Hsiao WC, Jee SH, Tsai TF, Yu HS, Lai JY, Young TH. Study on the effect of nylon-chitosan blended membranes on the spheroid forming activity of human melanocytes. Biomaterials 27:5079-88, 2006.
  24. Lin SJ, Jee SH, Hsiao WC, Yu HS, Tsai TF, Chen JS, Hsu CJ, Young TH. Enhanced cell survival of melanocyte spheroids in serum starvation condition. Biomaterials 27: 1462-1469, 2006.
  25. Lin SJ, Jee SH, Hsiao WC, Lee SJ, Young TH. Formation of melanocyte spheroids on the chitosan-coated surface. Biomaterials 26:1413-1422, 2005.
  26. Lee JN, Jee SH, Lo W, Chan CC, Dong CY, Lin SJ.The effect of depilatory agents as a penetration enhancer on human stratum corneum structures. Journal of Investigative Dermatology 128:2240-7, 2008. (Issue cover)
  27. Lin SJ, Jee SH, Kuo CJ, Wu RJ, Lin WC, Chen JS, Liao YH, Hsu CJ,  Tsai TF, Chen YF, Dong CY. Discrimination of basal cell carcinoma from normal dermal stroma by quantitative multiphoton imaging. Optics Letters 31: 2756-2758, 2006. (selected in Virtual Journals in Biological Physics Research)
  28. Lin SJ, Wu RJ, Tan HY, Lo W, Lin WC, Young TH, Hsu CJ, Chen JS, Jee SH, Dong CY. Evaluating cutaneous photoaging by use of multiphoton fluorescence and second harmonic generation microscopy. Optics Letters 30: 2275-7, 2005. (selected in Virtual Journals in Biological Physics Research)
  29. Tsai TH, Jee SH, Chan JY, Lee JN, Lee WR, Dong CY, Lin SJ. Visualizing laser-skin interaction in vivo by multiphoton microscopy.  Journal of Biomedical Optics 14: 024034, 2009.
  30. Lin MG, Yang TL, Chiang CT, Kao HC, Lee JN, Lo W, Jee SH, Chen YF, Dong CY, Lin SJ. Evaluation of dermal thermal damage by multiphoton autofluorescence and second harmonic generation microscopy. Journal of Biomedical Optics 11:064006, 2006.
  31. Lin SJ, Hsiao CY, Sun Y, Lo W, WC Lin, Jan GJ, Jee SH, Dong CY. Monitoring the thermally induced structural transitions of collagen using second harmonic generation microscopy. Optics Letters 30:622-4, 2005. (selected in Virtual Journals in Biological Physics Research)
  32. Wang CC, Li FC, Lin WC, Chen YF, Chen SJ, Lin SJ, Dong CY. Early development of cutaneous cancer revealed by intravital nonlinear optical microscopy. Applied Physics Letters 97: 113702, 2010.
  33. Tsai TH, Jee SH, Dong CY, Lin SJ. Multiphoton microscopy in dermatological imaging. Journal of Dermatological Science 56:1-8, 2009.
  34. Chan CC, Fan MY, Wan WH, Lin SJ*. A two-stepped culture method for efficient production of trichogenic keratinocytes. Tissue Engineering Part C Methods 21:1070-9, 2015.
  35. Wu YF, Wang SH, Wu PS, Sabrina Fan MY, Chiu HY, Tsai TH, Lin SJ*. Enhancing hair follicle regeneration by nonablative fractional laser: assessment of irradiation parameters and tissue response. Lasers in Surgery and Medicine 47:331-41, 2015.